Abstract: According to the special antifouling need of elastic base metal of the marine engineering equipment, a series of novel block polyether ester polyols based on PEG and caprolactonehad were prepared and the degradable polyurethane films were prepared by solution casting with a series of polyether ester polyols and cross linker agent. The hydrophilia and the degradation of the polyurethane films were investigated. The relationship between structure and degradable properties of polyurethane films were investigated. The degradable polyurethane marine antifouling paints were prepared by mixing cuprous oxide and the polyether ester polyols, and the controlled release mechanism of paints was investigated.