Abstract: Due to the good shear resistance, resistance to indentation, fracture resistance, surface ecotropic, permeability variability and energy absorbing, the mechanical metamaterials with negative Poisson's ratio are widely used in fields such as marine ships, aerospace, precision instruments, and engineering construction. The metamaterials have complex cell structure, and the traditional manufacturing techniques are difficult to meet the requirements of metamaterial sample manufacturing, therefore, the development of metamaterials is limited. With the rise of micro-nano manufacturing technology and 3D printing technology, it is possible to manufacture ultra-complex structural parts that are difficult to be completed by the traditional precision machining technology, and it also brings opportunities for the development of metamaterials. As the application of negative Poisson's ratio mechanical metamaterial expands in various industries, the existing negative Poisson's ratio mechanical metamaterial has become difficult to meet the needs of the market, and how to design more negative Poisson's ratio mechanical metamaterial has become an urgent problem to be solved. In this work, a novel negative Poisson's ratio mechanical metamaterial is designed by combining the compression and torsion module composed of chiral elements and the rotating polygon structure. The sample is made by 3D printing technology, and its compression performance is simulated and tested. It is concluded that the structure can realize the diversity representation of deformation characteristics by changing the cell connection mode and setting different initial configuration.