Abstract: The influences of interface on the tension-tension fatigue property of fiber reinforced plastic composite materials are studied by orthogonal experimental design and modifying the interface by changing the types of matrix resins and reinforcing materials and adopting coupling agent. The results show that the matching of matrix resins and reinforcing materials have great influence on the tension-tension fatigue performance of fiber reinforced plastic composite materials. The application of coupling agent into the modification of interface can improve the tension-tension fatigue performance of glass fiber reinforced composite materials.