Abstract: ANSYS software is used to analyze and study the parametric structure of Workbench ACP for high-pressure fully wound gas cylinders. The layer data of carbon fiber composite layer is parameterized and adjustable, and the combined analysis of the single material gas cylinder liner and carbon fiber composite layer models is realized. According to the feedback of simulation analysis results, the layering parameters are adjusted and the design of high pressure large volume fully wound cylinders is updated and optimized. The Workbench ACP parametric structure analysis research completes a large number of engineering winding tests in the way of simulation analysis, and the optimized design can effectively shortens the product design cycle and cost investment. The research provides a certain reference value for the reliability design of this type of gas cylinder.