Abstract: The axial tensile-compression fatigue tests are carried out on Al-Al-steel and Al-Ti-steel clad plates, aiming at the material selection and node design requirements of Al-steel transition joints for hull structures. The fatigue limit and S-N curve of the material are tested, and the fatigue fracture behavior and fracture position of the two Al-steel transition joints compared and analyzed. The results show that the fatigue limit of the Al-Al-steel clad plate is 28.8 MPa and that of the Al-Ti-steel clad plate is 55.0 MPa under the condition of the stress ratio of -1 and the axial tension-compression load. Under the condition of similar fatigue life, the latter can withstand greater stress than the former, and the resistance to fatigue expansion is stronger. The fatigue fracture of the Al-Al-steel clad plate mainly occurs in the 1060 pure aluminum layer, and the fatigue fracture of the Al-Ti-steel clad plate occurs in the 3003 aluminum alloy layer. The fatigue fracture position is closely related to the tensile strength of the Al-steel joint material.